Nanosponges as Drug Carriers for the Management of Psoriasis

Psoriasis is a chronic skin condition characterized by the hyperproliferation of keratinocytes in the epidermis, resulting in a high turnover rate of the epidermal cells. Apart from its physical manifestations, it also impacts an individual's psychological well-being. Its symptoms, such as pain, itching, and peeling, are more severe than those of other diseases, leading to a higher prevalence of depression and anxiety. Nanosponges are versatile nanoparticle platforms with porous, threedimensional structures that can effectively encapsulate and deliver a wide range of drugs and bioactive molecules, owing to their distinct capabilities, including controlled release patterns and the ability to target delivery. In this review, the advantages of nanosponges as a drug delivery system for treating the disease will be discussed.