Transferosomes as a Drug Carrier for the Management of Psoriasis

The autoimmune condition psoriasis is typified by hyperproliferation of keratinocytes, lesions, and silver-white scales inside the epidermis. Environmental and genetic factors both contribute to its cause. For psoriasis, several medication targets and focused treatments have been discovered. To lessen the symptoms of this illness, numerous target-specific medicines have also been created. Psoriasis is being treated using a variety of techniques, such as herbal remedies, nano-carrier therapy, and conventional therapy. In this regard, delivery through the transdermal route is an intriguing choice because it is safe and convenient. Since transferosomes have a bilayered structure that makes it easier to encapsulate lipophilic, hydrophilic, and amphiphilic drugs with higher penetration efficiencies than regular liposomes, they are a popular option for transdermal medication delivery for psoriasis. Because of their flexibility, they can flex and sneak through small pores that are significantly smaller than their actual dimensions, while remaining intact as a whole vesicle. This chapter aims to explain the concept of transferosomes, their mode of action, various methods of preparation, and their current applications in psoriasis therapy.