Physiological Significance of Mamsa Dhatu: An Ayurvedic Insight with Modern Correlations

Background: Mamsa Dhatu, or muscular tissue, is the third of the seven Dhatus in Ayurveda and is essential to the body's strength, protection, and structural support. Modern physiology clarifies its anatomical and functional parallels, whereas classical writings highlight its significance in health and illness. Objective: With an emphasis on its embryological genesis, characteristics, physiological functions, pathological alterations, and therapeutic significance, this paper examines Mamsa Dhatu from both Ayurvedic and contemporary viewpoints. Methods: With the help of reputable commentaries and contemporary biomedical literature, the study draws from Ayurvedic classics such as the Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, and Kashyapa Samhita. The digital repositories of AYUSH, Google Scholar, and PubMed were used to collect sources. Results: Prithvi and Jala Mahabhuta make up the majority of Mamsa Dhatu, which gives the body stability and unity. It adds to general strength and endurance while supporting ligaments, bones, and joints. In contemporary medicine, pathological alterations such Mamsa Kshaya (muscle wasting) and Mamsa Vriddhi (hypertrophy) correlate to diseases like myopathies, tumours, and metabolic disorders. Shodhana, Shamana, food, and exercise are examples of Ayurvedic therapies that closely resemble contemporary methods that incorporate physical training and nutrition. Conclusion: Our knowledge of muscle physiology, its problems, and treatment is enhanced when we examine Mamsa Dhatu from both an Ayurvedic and contemporary scientific perspective. There is potential for improving musculoskeletal research and clinical care with this integrative approach.