Tumor Location Significantly Correlates With PD-L1 Status in Patients With Small Sized Non-small Cell Lung Cancer

Anticancer Research 2026

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Authors: Takuma Tsukioka, Ryu Nakajima, Kyukwang Chung, SATOSHI OKADA, Kazuya Kishimoto, HIROYUKI KOCHI
DOI: 10.21873/anticanres.17998
Cited by: 0

Abstract

Background/Aim: Predicting programmed death-ligand 1 (PD-L1) expression in resectable lung cancer cases is highly significant for establishing treatment strategies. Although there were differences in tumor characteristics between central and peripheral lesions in non-small cell lung cancer (NSCLC), the relationship between tumor location and PD-L1 expression status has not been examined. We investigated the relationship between clinical background factors, including tumor location, and PD-L1 expression status. Patients and Methods: A total of 245 NSCLC patients whose tumors were measuring 3 cm or less in diameter and had a consolidation tumor ratio (CTR)

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Lung Cancer Diagnosis and Treatment Lung Cancer Research Studies

Publication details

Journal / source
Anticancer Research
Volume
46
Issue
2
Pages
911–916
Publication date
30 January 2026
Language
EN