Delayed Initiation of S-1 Adjuvant Chemotherapy Impairs Survival in Patients With Curatively Resected Pancreatic Cancer

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Authors: DONGHA LEE, Hirochika Toyama, Yoshihide Nanno, H Nakamura, Taisuke Okawa, Takuya Mizumoto, Jun Ishida, Masayuki Akita, KEISUKE ARAI, TOSHIHIKO YOSHIDA, Shinichi So, TSUYOSHI URADE
+6 more Kenji Fukushima, Shohei Komatsu, Sadaki Asari, HIROAKI YANAGIMOTO, Masahiro Kido, T. Fukumoto
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Abstract

Background/Aim: The prognostic impact of the timing of adjuvant chemotherapy initiation in patients with resected pancreatic cancer is unclear. Therefore, this study aimed to investigate whether delayed initiation of S-1 adjuvant chemotherapy affects the survival of patients with resectable pancreatic cancer. Patients and Methods: Patients who received S-1 adjuvant chemotherapy after undergoing R0/R1 resection were grouped according to whether adjuvant chemotherapy was initiated

Fields of Study & Subjects

Pancreatic and Hepatic Oncology Research Cholangiocarcinoma and Gallbladder Cancer Studies Gastric Cancer Management and Outcomes

Publication details

Journal / source
Anticancer Research
Volume
46
Issue
2
Pages
987–999
Publication date
30 January 2026
Language
EN