Investigation of the Relationship Between Adrenal Gland Signal Intensity and Age in Whole-body MRI/DWIBS

Background/Aim: To identify factors influencing adrenal signal intensity in whole-body magnetic resonance imaging/diffusion-weighted whole-body imaging with background body signal suppression (MRI/DWIBS). Patients and Methods: This retrospective study included patients who underwent whole-body MRI/DWIBS at our institution between April 2019 and April 2025 with no malignant tumor or history of a malignant tumor. Adrenal signal intensity and gland area were measured and analyzed according to sex and age. Results: The study included 22 male patients (average age of 58.2±11.7) and 38 female patients (average age of 55.9±15.4). The maximum signal intensity (max value) of the left adrenal gland on diffusion-weighted imaging was 1,885.5±352.0, and the mean gland area was 1,198±435.0 mm2 in male patients, and 1,517.1±429.5 and 760.5±325.6 mm2, respectively, in female patients. The median values for max value of the left adrenal gland on diffusion-weighted imaging were significantly larger in male patients (male: 1855 vs. female: 1,472, p