Ameliorative effects of Corchorus olitorius leaf ethanolic extract on letrozole-induced polycystic ovary syndrome (PCOS) in rats.

PubMed 2026 Open access

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Authors: Ekaette Sunday Udoh, Essiet Grace Akanimo, Victor Udo Nna, Umoren Inyang Arit, Ugbem Theophilius Ipeh, Lapeh Pierre Takem, Umiom Edem
DOI: 10.22038/ajp.2025.25627
Cited by: 0

Abstract

Objective: leaf extract on induced polycystic ovarian syndrome (PCOS) rats. Materials and Methods: day. Hormonal levels, glucose level, lipid profile, hematological indices, liver function, kidney function, and histopathological studies of the ovaries and uteri were all determined. Results: leaf extract showed its ameliorative effects in terms of normalizing the altered vaginal cytology, restoring most parameters, and improving the appearance of ovarian and uterine morphology. Conclusion: leaves ameliorate PCOS symptoms in the studied biochemical and histological parameters.

Fields of Study & Subjects

Ovarian function and disorders Phytoestrogen effects and research Seed and Plant Biochemistry

Publication details

Journal / source
PubMed
Volume
15
Issue
6
Pages
1623–1635
Publication date
9 January 2026
Language
EN