CPUK02 sensitizes U87 glioblastoma cell lines to TMZ treatment via autophagy flux inhibition.

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Authors: Hooman Rezaie, Sanaz Dastghaib, Morvarid Siri, Pooneh Mokarram, Mina Hemmati
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Abstract

expression might contribute to the enhanced TMZ sensitivity. This combination therapy is promising for TMZ-resistant cancers, but it needs further investigation.

Fields of Study & Subjects

Autophagy in Disease and Therapy Endoplasmic Reticulum Stress and Disease Ubiquitin and proteasome pathways

Publication details

Journal / source
PubMed
Volume
15
Issue
1
Pages
11–20
Publication date
1 January 2026
Language
EN