A comprehensive Review on Formulation, Characterization, Composition, Stability & Preparation, of Nanoemulsions

The use of Essential Oils (Eos) alone is limited due to their disadvantages such as high volatility, low stability, bioavailability and solubility. Therefore, Essential Oils are generally use in the form of nanoemulsions. The food and pharmaceutical sectors have shown a great deal of interest in essential oil-based nanoemulsions (EO-NEs) because of their improved stability, bioavailability, and functional properties. Nano-based emulsions havereceived considerable attention recently due to their physico-chemical properties and kinetic stability , attractive appearance. Furthermore, their rheological properties make them superior over counter parts. The ability of nanoemulsion to improve the solubility, bioavailability and stability of weakly water-soluble drugs has emerged their roles as promising drug delivery systems, drug administration and vaccine formulation, cosmetics, and food, it also has numerous applications in the field of agriculture. Nevertheless, their benefits, some concerns may represent obstacles that hinder their applications such as formulation complexity, stability issues and industrial production scale-up. To get beyond these hurdles and completely realize the potential of nanoemulsion in commercial and therapeutic applications, more research and innovation are need. This review intends to offer an overview of the formulation, Characterization, Composition, Stability & Preparation, of nanoemul sions specifically, recent literature has been examined in order to define the most common practices adopted (materials and fabrication methods), highlighting their suitability and effectiveness. Finally, relevant to some points such as advantages disadvantages, and applications of nanoemulsions.