Development and Validation of Stability Indicating RP-HPLC Method for the Estimation of Lasmiditan in tablet dosage form
Abstract
HPLC, in particular, offers high resolution, accuracy, and reproducibility, making it indispensable for routine quality control and advanced research applications. Method development in HPLC involves systematic selection and optimization of mobile phase composition, column chemistry, detection wavelength, and operational parameters to achieve reliable separation and quantification. Analytical method validation, guided by ICH and USP standards, ensures that developed methods meet essential criteria, including accuracy, precision, linearity, specificity, robustness, and sensitivity. Keywords: Lasmiditan, Development, RP-HPLC, Accuracy, linearity, Limit of detection (LOD) and Limit of quantification (LOQ).
Fields of Study & Subjects
Analytical Methods in Pharmaceuticals
Analytical Chemistry and Chromatography
Drug Solubulity and Delivery Systems
Publication details
- Journal / source
- Journal of Drug Delivery and Therapeutics
- Publisher
- Society of Pharmaceutical Tecnocrats
- Volume
- 16
- Issue
- 1
- Pages
- 36–42
- Publication date
- 15 January 2026
- Language
- EN