Histopathological Comparison of Placentas of Women with High and Normal BMI During Pregnancy

Objective: High body mass index (BMI) during pregnancy has been associated with adverse outcomes for the mother, fetus, and placenta. The effects of these adverse outcomes on the placenta in pregnant women with high BMI have not yet been histomorphologically characterized. Clarifying the effects of high BMI on placental function and determining necessary measures to protect maternal and fetal health is important. The aim of this study is to evaluate the possible structural and functional changes occurring in the placentas of women with normal weight and those with high BMI during pregnancy using hematoxylin-eosin (H&E) staining, and to compare their placentas histopathologically. Materials and Methods: Placental tissues were obtained from 45 normal, healthy pregnant patients with a BMI