Phytoconstituents in Herbal Toothpastes: Mechanisms for Plaque Control and Gingival Health
Abstract
The global rise in interest toward herbal oral care products has brought significant focus on the phytoconstituents present in herbal toothpastes. Unlike conventional formulations containing fluoride, triclosan, and chlorhexidine, herbal preparations utilize natural bioactive compounds such as flavonoids, tannins, terpenoids, alkaloids, and essential oils derived from plants like neem, clove, licorice, and miswak. These phytoconstituents exert antibacterial, anti-inflammatory, antioxidant, and plaque-inhibiting actions that contribute to maintaining gingival health. This review summarizes the mechanisms of plaque formation, the role of active phytoconstituents, their pharmacological actions, and compares them with conventional agents. Safety aspects, current evidence from clinical and laboratory studies, and future research prospects are also discussed to highlight the therapeutic potential of herbal-based oral care products. Keywords: Herbal toothpaste; Phytoconstituents; Dental plaque; Gingival health; Antimicrobial activity
Fields of Study & Subjects
Oral microbiology and periodontitis research
Ethnobotanical and Medicinal Plants Studies
Andrographolide Research and Applications
Publication details
- Journal / source
- Journal of Drug Delivery and Therapeutics
- Publisher
- Society of Pharmaceutical Tecnocrats
- Volume
- 16
- Issue
- 4
- Pages
- 177–184
- Publication date
- 15 April 2026
- Language
- EN