Chemical study and biological activities of Dalbergia baronii Baill. leaves (fabaceae): Antibacterial and antiplasmodial activity

Journal of Pharmacognosy and Phytochemistry 2026 Open access

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Authors: Ralaivaon-dratsitonta Jumaël Edith Fabrice, Andrianjato Tartin, Andrianarijaona Mamy, Robijaona Rahelivololona Baholy, Fatiany Pierre Ruphin
DOI: 10.22271/phyto.2026.v15.i1d.15743
Cited by: 0

Abstract

Chemical and biological studies were carried out on Dalbergia baronii Baill, an endemic species of Madagascar from the Fabaceae family [1]. Several secondary metabolites of interest were found, including phenolic compounds (tannins, flavonoids, coumarins, leucoanthocyanins) [2, 3]. Biologically, it was shown that the extract has specific antibacterial activity, particularly against Gram-positive bacteria such as Streptococcus pyogenes and Streptococcus pneumoniae, indicating noteworthy selectivity and a targeted therapeutic potential. In addition, significant antiplasmodial activity was observed, with inhibition of Plasmodium falciparum growth at an IC50 value of 7.86 µg/ml.

Fields of Study & Subjects

Phytochemistry and Biological Activities Phytochemical compounds biological activities Essential Oils and Antimicrobial Activity

Publication details

Journal / source
Journal of Pharmacognosy and Phytochemistry
Volume
15
Issue
1
Pages
318–322
Publication date
1 January 2026
Language
EN