Detection of ACCPA Levels in Patients with Proteus Mirabilis Urinary Tract Infection: Possible Implications for Rheumatoid Arthritis

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Authors: Noor H. Saleh, Maysaa S. M. Al-Shukri, Zakaria Moayad Al-Ghazaly
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Abstract

Objective: To investigate the anti-citrullinated protein antibodies (ACCPA) value for patients who have urinary tract infection (UTI) with Proteus mirabilis (P. mirabilis) and rheumatoid arthritis (RA) patients. Methods: Eighty serum samples were analyzed for antibodies to cyclic citrullinated peptides (Anti-CCP) by ELISA. The samples included 40 from patients with RA diagnosed according to the 2010 American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR) criteria, 20 from patients with UTI caused by P. mirabilis, and 20 from healthy controls. Results: ACCPA was significantly higher in RA patients (P

Fields of Study & Subjects

Rheumatoid Arthritis Research and Therapies Gout Hyperuricemia Uric Acid Systemic Lupus Erythematosus Research

Publication details

Journal / source
Journal of Contemporary Medical Sciences
Volume
12
Issue
1
Publication date
26 February 2026
Language
EN