The effectiveness of treatment of newly diagnosed and relapsed tuberculosis with HIV infection in a medical and correctional institution

The aim . To clarify the effectiveness of treatment for newly diagnosed and relapsed tuberculosis combined with HIV infection in patients in places of imprisonment. Materials and methods . 327 patients (men) with tuberculosis and HIV infection stages 4B, 4C and 5: Group 1 — 72.2% (n=262) with newly diagnosed tuberculosis, Group 2 — 17.9% (n=65) with relapse. To analyze the effectiveness of treatment, χ 2 was calculated with Yates correction for continuity between the indicators of the groups by treatment quarters. Results and discussion . In the first 3 months of treatment, bacterial excretion by sputum microscopy ceased in 41.7% (48/115) and 33.3% (11/33), in the 12th month of treatment in 63.5% (73/115) and 57.6% (19/33); in the first 3 months of treatment, bacterial excretion by sputum culture ceased in 42.4% (72/170) and 42.0% (21/50), in the 12 th month of treatment in 67.6% (115/170) and 62.0% (31/50); In the first 3 months of treatment, closure of decay cavities occurs in 26.5% (31/117) and 26.7% (12/45), in the 12 th month of treatment in 64.1% (75/117) and 55.6% (25/45) of newly diagnosed tuberculosis, respectively. Conclusion . In patients with tuberculosis combined with HIV infection in an anti-tuberculosis institution of the penitentiary service of Russia, the effectiveness of treatment for newly diagnosed and relapsed disease is practically the same.