Ultrasound semiotics of tumor thrombosis of leiomyosarcoma of the inferior vena cava: a prospective study

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Authors: Sergey N. Berdnikov, Mikael G. Abgaryan, Владимир Николаевич Шолохов, M. S. Makhotina, Aleksei E. Kalinin, Е. В. Тихонова
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Abstract

Introduction: Patients with tumor thrombosis of the inferior vena cava leiomyosarcoma should not be considered inoperable; they are subject to radical treatment, which can significantly prolong their lives. Only a multiparametric approach to diagnosis will allow clinicians to have a complete picture of the severity of the patient’s condition in order to make a decision on the choice of the optimal treatment method. Objective: Improvement of the results of ultrasound semiotics and the use of multiparametric ultrasound examination of tumor thrombosis of leiomyosarcoma of the inferior vena cava. Materials and methods: The study included 26 leiomyosarcomas of the IVC identified by CT with intravenous contrast, and 14 of them were patients with tumor thrombosis of the IVC. Results: In our observations, the main localization of the primary tumor of the inferior vena cava is the level of the infrarenal, cavarenal, and suprarenal segments of the IVC, and the upper border of the tumor thrombus is below the level of the diaphragm, and only in two cases there was an incomplete occlusion of the hepatic vein orifice. In all other cases, the apex of the tumor thrombus was determined at the level of the suprarenal segment of the IVC. The standard situation was the tumor germination of all layers of the IVC wall, regardless of localization and semicircle, the tumor thrombus in the IVC lumen originated from the main tumor mass and spread in the direction of blood flow. In the preliminary assessment, when comparing the data of complex ultrasound diagnostics (B-mode, shear pulse-wave elastography and elastometry) of the leiomyosarcoma of the IVC with tumor thrombosis and in comparison with the data of the study of the macropreparation — tumor and tumor thrombosis, there was a complete coincidence, where p

Fields of Study & Subjects

Sarcoma Diagnosis and Treatment Cardiac tumors and thrombi Ultrasound in Clinical Applications

Publication details

Journal / source
Diagnostic radiology and radiotherapy
Volume
16
Issue
4
Pages
71–78
Publication date
29 January 2026