Human insulin via MMP® for treating atrophic acne scars: a pilot study Insulina humana via MMP® para cicatrizes atróficas de acne: estudo piloto.

INTRODUCTION: Atrophic acne scars result from changes in the extracellular matrix during the inflammatory process and have a significant functional and psychosocial impact.Human insulin has favorable effects on tissue regeneration; however, its application via microinfusion of drugs into the skin (MMP®) to treat atrophic acne scars remains underexplored.OBJECTIVES: To evaluate the clinical effects of the application of human insulin via MMP® to treat atrophic acne scars.METH-ODS: this pilot, analytical, uncontrolled study included eight participants who underwent three biweekly sessions of MMP® with regular human insulin.RESULTS: The mean age of the patients was 29.3 ± 6.9 years; with six women (75.0%).A clinical improvement was observed with favorable evaluations in termos of pain and patient satisfaction.CONCLUSION: Patients exhibited clinical improvement in the appearance of atrophic acne scars following MMP® treatment with human insulin.Moreover, they reported a high degree of satisfaction.