Component-Resolved Diagnosis in IgE-Mediated Cow’s Milk Protein Allergy: Age-Stratified Analysis of Clinical Phenotypes and Predictive Value for Anaphylaxis

Background: Cow’s milk protein allergy (CMPA) is a prevalent pediatric food allergy with heterogeneous, age-related clinical manifestations, posing challenges to diagnosis and management. Component-resolved diagnostics (CRD) holds potential for precise evaluation, but its age-stratified value remains to be clarified. Methods: A cross-sectional, single-center study was conducted on 131 children with IgE-mediated CMPA, who were divided into