Vertebral Body-Level Increased Signal Intensity in Cervical Ossification of the Posterior Longitudinal Ligament: Association with Segmental Hypermobility and Surgical Outcomes

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Authors: Yuta Yamamoto, Takuhei Kozaki, Yasutsugu Yukawa, Hiroshi Iwasaki, Shunji Tsutsui, Masanari Takami, Keiji Nagata, Yuyu Ishimoto, Masatoshi Teraguchi, Shizumasa Murata, Ryuichiro Nakanishi, Takahiro Kozaki
+2 more Hiroshi Hashizume, Hiroshi Yamada
Cited by: 0

Abstract

Introduction: Increased signal intensity (ISI) on T2-weighted magnetic resonance imaging at the vertebral body level in cervical ossification of the posterior longitudinal ligament (OPLL) may reflect dynamic cord compression. This study investigated the prevalence, radiographic characteristics, and surgical outcomes associated with vertebral body-level ISI in patients with OPLL. Methods: This retrospective study analyzed 95 patients with cervical OPLL who underwent surgery between 2013 and 2022. Patients were categorized on the basis of ISI location: group D (disc level, n=52) and group B (vertebral body level, n=23). Radiographic parameters including cervical alignment, range of motion (ROM), and K-line status were evaluated. Clinical outcomes were assessed using Japanese Orthopaedic Association (JOA) scores at 2-year follow-up. Results: Vertebral body-level ISI was observed in 24.2% of the entire cohort, accounting for 30.7% of patients with ISI. Group B indicated significantly greater local ROM (10.3±2.2° vs 5.8±2.6°, p

Fields of Study & Subjects

Cervical and Thoracic Myelopathy Spine and Intervertebral Disc Pathology Musculoskeletal pain and rehabilitation

Publication details

Journal / source
Spine Surgery and Related Research
Volume
10
Issue
4
Pages
539–547
Publication date
15 February 2026
Language
EN