The Impact of Ancestry on Performance of Type 1 Diabetes Genetic Risk Scores: High Discrimination Performance Is Maintained in African Ancestry Populations, but Population-Specific Thresholds May Improve Risk Prediction

Diabetes Care 2026 Open access

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Authors: Steven Squires, Jean Claude Katte, Dana Dabelea, Catherine Pihoker, Jasmin Divers, Eugène Sobngwi, Moffat Nyirenda, Raymond J. Kreienkamp, Angela D. Liese, Amy S. Shah, Lawrence M. Dolan, Kristi Reynolds
+8 more Maria J. Redondo, William Hagopian, Segun Fatumo, Mesmin Dehayem, Andrew T. Hattersley, M. Weedon, Jones AG, R. Oram
DOI: 10.2337/dc25-1833
Cited by: 2
References: 5

Fields of Study & Subjects

Genetic Associations and Epidemiology Diabetes and associated disorders Pancreatic function and diabetes

Publication details

Journal / source
Diabetes Care
Publisher
American Diabetes Association
Volume
49
Issue
3
Pages
e33–e35
Publication date
16 January 2026
Language
EN