Is the primary open angle glaucoma finding connected with kidney function? Results from several Basra City hospitals

BACKGROUND: Chronic kidney disease (CKD) is defined as a GFR of under sixty milliliter/minute per 1.73 m2 of the body or a urine albumin excretion of more than thirty milligrams per gram that has lasted for more than three months and has negative health effects; on another hand primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy resulting in retinal ganglion cell (RGC) death and irreversible visual impairment. The aim of this study was to investigate the connection between CKD and POAG.METHODS: Three thousand and two hundred people are included in this investigation; they are split into 2 groups. POAG (N.=186) and non-POAG (N.=3014). This study is carried out at multiple medical centers in Basra City (Iraq).RESULTS: We found that POAG patients were significantly older than non-POAG patients. Moreover, male gender, hypertension, and diabetes were significantly more frequent among POAG patients. However, compared to non-POAG patients, POAG patients had a considerably greater IOP. According to this study, POAG patients had significantly increased occurrence of CKD. In addition, POAG patients had a significantly greater level of urea and creatinine than non-POAG patients. However, eGFR was considerably lower in POAG individuals compared to non-POAG patients. Patients with POAG experienced higher rates of proteinuria than non-POAG patients, although nothing had changed that would be considered statistically significant. The prevalence of POAG and CKD stages are significantly correlated.CONCLUSIONS: Based on our research, we can say that kidney function and POAG were significantly correlated.