Diagnostic value of diffusion-weighted imaging, apparent diffusion coefficient and dynamic contrast enhanced values in 3T head MRI on glioma grading

BACKGROUND: Gliomas are the most common primary intracranial tumors, graded I-IV based on histopathological and imaging features. Diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC), and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) are advanced MRI techniques aiding glioma grading. ADC reflects tissue microstructure, while DCE-MRI evaluates perfusion and angiogenesis. These methods correlate with glioma grades, distinguishing low- and high-grade tumors. This study investigates DWI, ADC, and DCE-MRI parameters in glioma grading using 3T MRI in Makassar.METHODS: This cross-sectional study analyzed retrospective MRI data from Makassar (2020-2024), including patients with glioma confirmed via surgery and pathology. Statistical tests assessed DWI, ADC, and DCE correlations with glioma grading. Sensitivity, specificity, and cutoff points were determined using receiver operating characteristic (ROC) curves; P