Doxycycline postexposure prophylaxis: a cross-sectional survey on knowledge, attitudes and prescribing practices among Italian dermatologists of sexually transmitted infection centers
Abstract
BACKGROUND: Postexposure prophylaxis with doxycycline (Doxy-PEP) significantly reduces incidence of certain bacterial STIs in men who have sex with men (MSM) and individuals with recurrent STIs. We assessed knowledge, attitudes, and clinical experience regarding Doxy-PEP of dermatologists specialized in STI prevention, diagnosis, and treatment in Italy. METHODS: A cross-sectional survey was conducted in March 2025 using a questionnaire to investigate knowledge of Doxy-PEP prescribing protocols and patient eligibility, perceptions of its efficacy against several STIs, personal experience in Doxy-PEP prescription and drawbacks, opinions on its future use. RESULTS: Thirty-six dermatologists participated. All knew about Doxy-PEP. The population most frequently considered eligible for Doxy-PEP was represented by MSM (69.4%). Respondents would prescribe Doxy-PEP after recent exposure (
Fields of Study & Subjects
Reproductive tract infections research
HIV/AIDS Research and Interventions
Syphilis Diagnosis and Treatment
Publication details
- Journal / source
- Italian Journal of Dermatology and Venereology
- Publisher
- Edizioni Minerva Medica
- Volume
- 161
- Issue
- 2
- Pages
- 120–125
- Publication date
- 1 March 2026
- Language
- EN