Bilateral root absence of permanent first molars: literature review and case report.

AIM: This case report and literature review aim to elucidate the rare occurrence of bilateral root absence in permanent first molars, emphasizing its clinical implications, diagnostic challenges, management, and possible association with systemic conditions. A unique case involving a 13-year-old male diagnosed with atypical hemolytic uremic syndrome (aHUS) is presented to illustrate these points. METHODS: A comprehensive review of existing literature was conducted to explore the etiology, diagnosis, and management strategies for root absence. In addition, the detailed case study of the patient with aHUS and root absence of all four permanent first molars complements the review, providing insights into systemic impacts on dental development. CONCLUSION: This report emphasizes the need for a multidisciplinary approach in diagnosing and managing dental anomalies associated with systemic diseases. Further research is recommended to understand the systemic influences on dental root development and improve patient outcomes.