The Immunological detection of Rubella virus among aborted women in Diyala province, Iraq

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Authors: Haneen Faleh Hassan, Zainab Alzubaidy, Rana F.Mahmood, AishaK. Hadi
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Abstract

German measles is a public illness that can cause congenital rubella syndrome (CRS) and abortion, among other devastating consequences for expectant mothers. The sickness is brought on by the rubella virus. The goal of this study was to determine the prevalence of rubella virus antibodies among aborted women in Diyala province, Iraq. In the current study, 120 samples were taken from three groups: pregnant women with previous abortion, non-pregnant women with previous abortion, and healthy pregnant women without abortion as a control group. Each group consisted of 40 women. The ELISA technique was used to measure rubella virus IgG and IgM antibodies in serum samples obtained from the Al-Batool Hospital laboratory. A questionnaire was used to collect data on clinical and demographic characteristics. The results indicated that the seropositivity of RV-IgM among pregnant women with abortion and healthy pregnant women was 0%, but the seropositivity of RV-IgM among non-pregnant women with prior abortion was 2.5%. The RV-IgG levels were 80% among pregnant women who have had prior abortions, 75% in non-pregnant women with prior abortions, and 82.5% in healthy pregnant women without abortion. The study found that women with a history of miscarriage had high levels of rubella IgG antibodies, indicating that they had previously been exposed to the rubella virus or vaccination state. The low incidence of IgM antibodies suggests a limited number of recent infections. These findings highlight the necessity of rubella immunization and surveillance in women of reproductive age to avoid rubella-related problems during pregnancy.

Fields of Study & Subjects

Virology and Viral Diseases Vaccine Coverage and Hesitancy Mosquito-borne diseases and control

Publication details

Journal / source
Academic Science Journal
Volume
4
Issue
1
Pages
26–32
Publication date
30 January 2026
Language
EN