Polyauxic Modeling Platform (v1.0.0)

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Authors: Gustavo Mockaitis
Cited by: 0

Abstract

Polyauxic Modeling Plataform is an open-source Python package designed for the robust kinetic modeling of mono- and polyauxic microbial growth. Addressing the limitations of standard single-phase analysis, this software implements semi-mechanistic reformulations of Boltzmann and Gompertz equations to extract biologically interpretable parameters from complex datasets. The computational workflow integrates a hybrid optimization pipeline, combining Differential Evolution for global search with L-BFGS-B for local refinement, alongside the ROUT method for outlier detection and information criteria (AIC, BIC) for automated phase selection. This modular framework ensures reproducibility and numerical stability, providing researchers in environmental biotechnology a powerful tool to analyze multiphasic substrate degradation dynamics.

Publication details

Journal / source
Code Ocean
Publication date
1 January 2026
Language
EN