Indolent systemic mastocytosis with response to phototherapy in a patient with other non-hematologic neoplasms: a therapeutic challenge
Abstract
Mastocytosis is a rare clonal hematopoietic disorder characterized by the proliferation of neoplastic mast cells in the skin or other organs, including the bone marrow. It is classified into cutaneous, systemic, and mast cell sarcoma. Treatments focus on symptoms control or eliminating mast cells, with KIT inhibitors like midostaurin and avapritinib being effective therapies. Phototherapy has proven effective in symptomatic control in indolent systemic mastocytosis as in the presented case, improving quality of life.
Fields of Study & Subjects
Mast cells and histamine
Gastrointestinal Tumor Research and Treatment
Histiocytic Disorders and Treatments
Publication details
- Journal / source
- Revista Medicina Cutánea Ibero-Latino-Americana
- Volume
- 53
- Issue
- 92
- Publication date
- 13 January 2026
- Language
- EN