Vancomycin-induced drug rash with eosinophilia and systemic symptoms syndrome: a case report

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is an uncommon but potentially life-threatening cutaneous hypersensitivity reaction characterized by extensive mucocutaneous eruption, fever, hematologic abnormalities, including eosinophilia and/or atypical lymphocytosis, and extensive organ involvement.Here, we present a rare case of DRESS syndrome in a female patient with burn injuries, following vancomycin therapy for methicillin-resistant Staphylococcus aureus infection.According to the RegiSCAR diagnostic criteria, the case was classified as definite DRESS.Clinical resolution was achieved with the timely initiation of methylprednisolone and antihistamine therapy. Keywords: Drug reaction with eosinophilia and systemic symptoms syndrome