Oxygen-induced hypercapnia in patients with exacerbations of chronic obstructive pulmonary disease: pathogenesis, diagnosis and prevention in emergency medical care (review)

The purpose of the study : conducting an analysis of periodical medical literature on the problem of the occurrence of oxygen-induced hypercapnia in patients with severe chronic and acute respiratory failure (RF) and its significance in providing emergency care to patients with chronic obstructive pulmonary disease (COPD). Objectives of the study . 18 articles on the subject of the review were analyzed. The results of the study . During emergency medical care (EMC), patients with respiratory failure are at risk of developing complications from oxygen therapy, such as increased blood carbon dioxide levels, which can significantly worsen the prognosis. This complication is particularly likely in severely ill patients with underlying hypercapnia associated with obstructive airway disease. Inappropriately high oxygen flow during inhalation plays a significant role in the development of this complication. Conclusion . This analysis of literature may have practical importance for medical staff of ambulance brigades, as well as for physicians in hospital›s emergency room when providing medical care to patients with worsening bronchoobstructive diseases.