Prevalence, diagnosis, and management of febrile seizures in children: a systematic review

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Authors: Maher S Shalabi, Muhannad Ahmed Nazal Alhazmi, Mussab Z Almaghrabi, Renad Alkenedri, Rena Aljahdli, Reema Saeed Almater, Ruba Murayyi, Rawan Al-Qahtani, Fatoon Alamri, Lamia Ahmed M. Saddah
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Abstract

Febrile seizures (FS) are the most common type of pediatric seizures, affecting 2-5% of children between six months and five years worldwide. Scientific research in recent years has paved the way for the exploration of many new tools to improve early assessment. Despite these advances, there is still uncertainty about how common different forms of febrile seizures are, which risk factors matter most, and which investigations truly help guide care. The review followed the PRISMA 2020 guidelines, and was analyzed using RevMan version 5.4.0. The Newcastle–Ottawa Scale (NOS) was applied to evaluate the methodological quality of included observational studies, and the Cochrane Risk of Bias tool was used to assess randomized studies. This systematic review compiled recent findings from 11 studies on prevalence, diagnostic indicators, and management. The progression to febrile status epilepticus was linked to younger age (

Fields of Study & Subjects

Epilepsy research and treatment Infectious Encephalopathies and Encephalitis Neurological and metabolic disorders

Publication details

Journal / source
International Journal of Medicine in Developing Countries
Pages
408–416
Publication date
1 January 2026