Search for correlations in raman, diffuse reflectance, and fluorescence spectroscopy data from intracranial tumors
Abstract
The task of developing a decision support system in neurooncology based on optical-spectral analysis of intracranial tumor tissue is associated with several challenges inherent in working with biomedical data. These include the high dimensionality of the feature vector with a relatively small sample size, data gaps, and sample imbalances due to the varying frequencies of various diagnoses. Analysis of correlations between features of the tumors under study will allow both the restoration of data gaps and their augmentation (artificial expansion of the training dataset by creating modified versions of existing examples). This paper presents an analysis of the dependence of various optical-spectral characteristics on the tumor cell/tissue content in the sample and the cross-correlations between various features.
Fields of Study & Subjects
Optical Imaging and Spectroscopy Techniques
Optical Polarization and Ellipsometry
Optical Coherence Tomography Applications
Publication details
- Journal / source
- Biomedical Photonics
- Publisher
- Russian Photodynamic Association
- Volume
- 14
- Issue
- 4
- Pages
- 22–33
- Publication date
- 12 February 2026
- Language
- RU