Two new cucurbitane-type triterpenoids fromthe peel of Trichosanthes kirilowii
Abstract
Two new cucurbitane-type triterpenoids (1-2) and one known compound (3) were obtained from the ethyl acetate extract of Trichosanthes kirilowii Maxim. The structures of these compounds were elucidated on the basis of spectroscopic data analysis and comparison with spectroscopic data in the literature. All compounds were evaluated for anti-inflammatory activity in LPS-induced RAW264.7 cells. Compounds 1 and 2 could inhibit the secretion of IL-6, TNF-α, and NO, with IC50 values ranging from 34.82±1.54 to 86.14±1.94 μM
Fields of Study & Subjects
Natural product bioactivities and synthesis
Phytochemistry and Biological Activities
Advances in Cucurbitaceae Research
Publication details
- Journal / source
- Records of Natural Products
- Volume
- 20
- Issue
- 1
- Publication date
- 10 February 2026
- Language
- EN