Diagnosis and therapy of onychomycosis caused by Trichophyton Schoenleinii and yeast-like fungi of the Candida genus

The article describes a clinical case of diagnosis and treatment of onychomycosis caused by combined flora — the causative agent of favus Trichophyton schoenleinii and yeast-like fungi of the Candida genus. An 85-year-old female patient was examined, who was under observation for 14 days in the 24-hour inpatient department of the State Budgetary Healthcare Institution of Bashkortostan “Republican Skin and Venereal Diseases Dispensary” in Ufa. Complaints and medical history were collected, physical examination, microscopic examination and microbiological culture of pathological material, systemic and topical treatment were performed. As a result, microscopy done twice revealed mycelium and yeast-like cells, and culture results revealed T. schoenleinii. The treatment resulted in regression of clinical manifestations. In this case, the clinical picture was characterized by a prolonged, subtle disease course, a combination of two pathogens, and a slow response to therapy. Patients’ comorbidity, elderly age, and subtle clinical symptoms are important factors of prolonged onychomycosis, multiple lesions of the nail plates, and the need for longer and combined treatment.