The Role of Serum Vitamin D in Rheumatoid Arthritis: Correlation with Disease Activity and Neuropathic Pain

Background: Vitamin D deficiency is common in rheumatoid arthritis and may influence inflammatory activity and pain processing. Objective: To evaluate the relationship between serum vitamin D levels, disease activity, and neuropathic pain in rheumatoid arthritis patients. Methods: A cross-sectional study of 120 rheumatoid arthritis patients assessed serum vitamin D levels, DAS28 disease activity, and neuropathic pain using DN4 scores. Results: Vitamin D deficiency was significantly associated with higher DAS28 scores and increased prevalence of neuropathic pain. Conclusion: Low serum vitamin D levels are linked to greater disease activity and neuropathic pain in rheumatoid arthritis.