Adverse Drug Reactions Associated with Psychotropic Medications in Neuropsychiatric Patients: A Retrospective Study

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Authors: Kumar Haraprasad Misra, Ananta Charan Meher, Saswat Satapathy
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References: 1

Abstract

Background: Chronic mental illnesses frequently necessitate long-term, ongoing medication. It is well recognized that using these drugs might have negative side effects. An adverse drug reaction (ADR) can have a major negative effect on a patient's quality of life if it is not identified. For family and community physicians who are currently in practice, their prevention and monitoring are essential. Therefore, the current study was conducted to determine the pattern of adverse drug reactions (ADRs) reported as a result of psychiatric medication. Method: The purpose of this retrospective observational study is to examine every spontaneous adverse drug response (ADR) that was reported during a 12-month period from the psychiatry department to the ADR Monitoring Center at SRM Medical College in Bhwanipatna. Results: There were 200 reported ADRs. The majority of the ADRs were observed from antipsychotics (47%) followed by antidepressants (21%) and Mood stabilizers medicines (38%). The most common ADR reported was sedation, EPS, and tremors (36%) followed by metabolic & weight gain (20%), gastrointestinal (36%), and cardiovascular (12%). Conclusion: Understanding common adverse drug reactions (ADRs) aids in the better treatment of illnesses and psychotropics, as they have a variety of common ADRs. Early detection and timely action can aid the community physicians in the proper treatment of the patients and rational use of pharmaceuticals.

Fields of Study & Subjects

Pharmacovigilance and Adverse Drug Reactions Schizophrenia research and treatment Pharmaceutical Practices and Patient Outcomes

Publication details

Journal / source
International Journal of Current Pharmaceutical Review and Research
Volume
18
Issue
01
Publication date
25 January 2026
Language
EN