Comparative Study of TSH and Prolactin in PCOS Subjects: A Case Control Study

Background: To assess serum TSH and Prolactin in women with PCOS in comparison with healthy women as controls and to find correlation between TSH & Prolactin in PCOS subjects. Methods: A comparative study including 30 women diagnosed as PCOS and 30 age and BMI matched healthy women as controls was conducted. The age group for the study was 18-35 years. Fasting blood samples were drawn to measure serum thyroid stimulating hormone (TSH) and prolactin. Results: Mean TSH and prolactin were found elevated in the PCOS cases compared to controls but they were not statistically significant. No significant correlation was found between TSH and prolactin. Conclusion: We could not find any significant correlation between serum TSH and serum prolactin. Further, studies with larger number of PCOS subjects will be beneficial. However monitoring of Prolactin and TSH in PCOS should be done.