A Clinico-Epidemiological Study of Elderly Breast Cancer with Special Reference to ER/PR Positivity

Background: Breast cancer prognosis and treatment outcomes are poorly understood. The clinicoepidemiological component of breast cancer with ER/PR positivity is the focus of this investigation. Methods: A retrospective analysis of patients with breast cancer aged ≥70 years was conducted at Government Medical College and Hospital in Bettiah, West Champaran, Bihar, between March 2025 and August 2025. Disease-free survival (DFS) and Kaplan Meir overall survival (OS) analysis were performed and associated with various prognostic markers. Results: 139 of the 186 elderly individuals were examined. With a mean age of 75, the median age at diagnosis was 73.4 years. The majority of patients (70.4%) had a co-morbidity score of < 2, were from metropolitan regions (89.2%), had a performance status of 1-2 (90.6%), and were between the ages of 70 and 74. In stages III and IV, 43.9% was shown. PR and ER were 75.5% and 83.4%, respectively. With a 62.6% modified radical mastectomy, a 15.1% conservative lumpectomy, and axillary clearance, surgery was performed in 77.7% of cases. The majority of the treatment consisted of hormones (79.9%), followed by radiation (47.5%) and chemotherapy (18.7%). The 5-year OS was 52%, and the DFS was 53.4%. Metastatic patients had a median progression-free survival (PFS) of four months. The DFS was significantly affected by performance status (PS), tumor stage, and presence of metastasis. (P-value = 0.018,