Association of Serum Catecholamine Concentrations with Heart Rate Variability in Patients with Chronic Heart Failure

Background: In order to identify higher-risk patients who might be the focus of additional treatment measures, a wide range of factors related to CHF can be assessed. By doing a bedside examination, it is quite simple to identify patients who exhibit symptoms and signs while at rest. Even with the best medical care, these patients still have an annual mortality rate of more than 40%, but their share of the overall heart failure population is quite modest. Objectives: In patients with chronic heart failure, the study sought to determine the association between HRV parameters and blood catecholamine levels as well as the usefulness of these measurements in indicating autonomic dysfunction and the severity of the condition. Materials and Methods: It was a retrospective, observational study. The study was carried out at a tertiary care centre. The study data that was retrieved was for one year. Data from 184 participants were retrieved for the study. Patients 18 years of age and older who had a diagnosis of chronic heart failure verified by clinical assessment and echocardiography and whose medical records had information on heart rate variability, blood catecholamine levels, and NYHA functional class were included in the study. Results: A significant proportion of patients (64.1%) demonstrated reduced left ventricular ejection fraction (