Association Between Serum Iron Indices and Neurodevelopmental Delay (NDD) in Children

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Authors: Patel Vishvaben Narendrabhai, Bhavikaben Jayantilal Maru, Amiben Manojbhai Patel
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Abstract

Background: Neurodevelopmental disorders such as autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), and intellectual disability (ID) are commonly associated with nutritional deficiencies, including altered iron status. Iron plays a critical role in brain development, and disturbances in iron metabolism may influence neurodevelopmental outcomes. This study aimed to evaluate differences in serum iron indices among children with different neurodevelopmental disorders. Methods: This hospital-based observational study included 186 children aged 4–12 years diagnosed with ASD, ADHD, or ID. Neurodevelopmental diagnoses were established using standardised assessment tools. Serum iron, serum ferritin, and serum transferrin levels were measured using standard laboratory methods. Iron parameters were compared across the three diagnostic groups using appropriate statistical analyses, with a p-value

Fields of Study & Subjects

Iron Metabolism and Disorders Trace Elements in Health Autism Spectrum Disorder Research

Publication details

Journal / source
International Journal of Current Pharmaceutical Review and Research
Volume
18
Issue
01
Publication date
25 January 2026
Language
EN