Comparison of Single-Stage Vs two-Stage Revision Surgery in Infected Implants
Abstract
Introduction: Periprosthetic joint infection (PJI) is a catastrophic complication of arthroplasty, necessitating high- stakes revision surgery. While two-stage revision has historically been the "gold standard," single-stage revision is increasingly debated for its potential functional benefits and reduced morbidity. Methods: This prospective comparative study evaluated 30 patients (n=15 single-stage; n=15 two-stage) over a 6-month follow-up period to assess infection eradication rates and early functional recovery. Results: Preliminary 6-month data indicate that the single-stage group achieved an infection eradication rate of 93.3% (14/15) compared to 86.6% (13/15) in the two-stage group (p > 0.05). The single-stage cohort demonstrated significantly earlier return to weight-bearing and higher functional scores (Oxford Hip/Knee Score) at the 3-month interval (p < 0.05) Conclusion: Single-stage revision is a viable and potentially. superior alternative for early functional recovery in selected PJI cases, though longer-term follow-up is required to confirm chronic suppression success.
Fields of Study & Subjects
Orthopedic Infections and Treatments
Orthopaedic implants and arthroplasty
Infectious Diseases and Tuberculosis
Publication details
- Journal / source
- International Journal of Current Pharmaceutical Review and Research
- Volume
- 18
- Issue
- 02
- Publication date
- 22 February 2026
- Language
- EN