Analysis of Diagnostic Accuracy of Computed Tomography Scan in Mediastinal Masses: A Cross-sectional Study

Background: From benign and malignant tumors, cysts, vascular abnormalities, and lymph node masses to diffuse lesions including pneumomediastinum, mediastinitis, mediastinal fibrosis, and encysted pleural effusion, mediastinal diseases encompass a broad spectrum of pathology. The basic aim of the study is to analyse the diagnostic accuracy of computed tomography scan in mediastinal masses assuming histopathological findings as gold standard. Methods: This cross sectional study was conducted in Department of Radiology, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar from July 2025 to December 2025. After taking informed consent, computed Tomography was performed on CT scanner before and after intravenous contrast administration. Results: Age range in this study was from 25-65 years with mean age of 48.57 ± 10.53 years. Majority of the patients 58.78% were between 46-65 years of age as shown in Table 1. Out of these 148 patients, 82 (55.41%) were males and 66 (44.59%) were females with ratio of 1.2:1. Mean duration of disease was 8.39 ± 4.78 months (Table 2). Mean size of mass was 5.21 ± 2.45 cm. Conclusion: It is concluded that computed tomography is a highly sensitive and accurate non-invasive modality for differentiating malignant and benign mediastinal masses, and has not only dramatically improved our ability of accurate diagnosis of mediastinal masses but also improved patient care by timely and proper treatment.