Panorama of Soft Tissue Tumours at a Tertiary Care Centre in Bihar: A Retrospective Observational Study

Objective and Aim: Soft tissue tumors (STTs) represent a heterogeneous group of neoplasms with diverse histogenesis, biological behavior, and clinical outcomes. The present study aims to evaluate the spectrum, frequency, demographic distribution, anatomical location, and histopathological patterns of soft tissue tumors diagnosed at a tertiary care center in Bihar, India, with special emphasis on benign–malignant correlation and clinicopathological characteristics. Materials and Methods: This retrospective observational study was conducted in the Department of Pathology at a tertiary care teaching hospital in Bihar over a period of five years (January 2019–December 2023). All histopathologically confirmed cases of soft tissue tumors were included. Tumors were classified according to the WHO Classification of Soft Tissue and Bone Tumors (2020). Statistical analysis was performed using SPSS version 26.0. Descriptive statistics, chi-square test, and logistic regression analysis were applied. Results: A total of 312 cases of soft tissue tumors were analyzed. Benign tumors constituted 76.9%, intermediate tumors 7.4%, and malignant tumors 15.7%. The most common benign tumor was lipoma (38.1%), while undifferentiated pleomorphic sarcoma (21.4%) was the most frequent malignant tumor. Malignant tumors were significantly associated with age >40 years (p