To Evaluate Diastolic Dysfunction and Left Ventricular Mass in Asymptomatic Normotensive ATYPE 2 Diabetes Mellitus

Background and Objectives: The world today is witnessing an epidemic of diabetes mellitus. Globally and nationally, diabetes and its complications have become the most important contemporary and challenging health problem. It is estimated that there will be more than 200 million diabetics in the world within the next 10 years. India has already become the diabetes capital of the world with over 30 million affected patients that is alarmingly just a tip of the iceberg and is expected to touch the 69.9 million marks in 2025. To evaluate Diastolic Dysfunction in asymptomatic normotensive Type 2 Diabetes Mellitus. To study left ventricular mass in asymptomatic normotensive Type 2 Diabetes Mellitus. Material and Methods: Study will be conducted in outp atient department of VMMC and Safdarjung Hospital. Cross sectional observational study. A total of 100 subjects,50 Diabetic normotensive patient and 50 nondiabetic healthy individuals satisfying the inclusion and exclusion criteria were included in this study. Conclusion: In our study diastolic dysfunction and LVM was present in 56% and 48% respectively in asymptomatic normotensive type 2 DM subjects. Asymptomatic normotensive type 2 DM had significantly high prevalence of diastolic dysfunction and left ventricular mass as compared to healthy subjects. LV diastolic dysfunction and left ventricular mass were correlated with the age, gender, HbA1c, duration of diabetes, BMI, smoking, dyslipidemia. After univariate analysis of various risk factors for diastolic dysfunction it was found that poor glycemic control (HbA1c), duration of diabetes, smoking, dyslipidemia was significantly associated with diastolic dysfunction(P0.05).