Association of High Sensitivity C - reactive protein and Serum Triglyceride Levels with Severity of Acute Pancreatitis: A Prospective Observational Study

Background: Acute pancreatitis (AP) is a potentially life-threatening condition with varying severity. Early identification of severe cases is crucial for improving outcomes. This study aimed to evaluate the role of highsensitivity C-reactive protein (hs-CRP), and serum triglyceride levels in predicting the severity of AP. Methods: A cross-sectional study was conducted on 125 patients diagnosed with AP. Serum calcium, hs-CRP, and triglyceride levels were measured within 24-48 hours of admission. Patients were classified into mild, moderately severe, and severe AP based on the Revised Atlanta Classification. Statistical analysis was performed to assess the correlation between these biomarkers and disease severity. Results: The mean age of patients was 50±15 years, with a male predominance (72.8%). Alcohol was the most common etiology (60%), followed by gallstones (25%). Severe AP was associated with higher hs-CRP (337±21 mg/L) and triglyceride levels (359±171 mg/dL) compared to mild and moderate AP (p