Comparison of healing outcomes of MTA and Biodentine as root end fillings in surgical Endodontics

Background: Successful periapical surgery depends largely on the biological and sealing properties of the rootend filling material. Mineral Trioxide Aggregate (MTA) has long been considered the gold standard; however, Biodentine, a newer calcium silicate–based material, has gained popularity due to its improved handling and shorter setting time. Aim: To compare the healing outcomes of MTA and Biodentine as root-end filling materials in surgical endodontics. Materials and Methods: This prospective randomized controlled clinical trial included 100 patients requiring periapical surgery. Participants were randomly allocated into two groups: Group I (n=50) received MTA as the root-end filling material, and Group II (n=50) received Biodentine. Standardized apicoectomy and retrograde cavity preparation were performed. Clinical and radiographic evaluations were conducted at 3, 6, and 12 months. Healing was assessed using clinical parameters and the Periapical Index (PAI) scoring system. Data were analyzed using Chi-square test and independent t-test, with p0.05). Complete radiographic healing was observed in 76% of MTA cases and 84% of Biodentine cases. Mean lesion size reduction was significantly greater in the Biodentine group (p=0.04). Conclusion: Both MTA and Biodentine demonstrated favorable clinical and radiographic healing following periapical surgery. Although Biodentine showed slightly improved radiographic outcomes, overall success rates were comparable, suggesting that Biodentine is a reliable alternative to MTA for root-end filling in surgical endodontics