The critical role of pharmacovigilance in monitoring drug-induced QT prolongation
Abstract
In the recent cross-sectional study 1 on QT interval prolongation in schizophrenia published in the June issue of the Indian Journal of Medical Research, the authors have done a remarkable job in highlighting the prevalence of QTc prolongation in patients with schizophrenia, a serious cardiac adverse effect of antipsychotic medications. 1 Their findings, which report QTc prolongation 3.4% of participants using Fridericia's formula and 6.8% using Bazett's formula, are significant as they underscore a potentially fatal cardiac risk, Torsades de Pointes (TdP).
Fields of Study & Subjects
Cardiac electrophysiology and arrhythmias
Pharmacovigilance and Adverse Drug Reactions
Drug-Induced Ocular Toxicity
Publication details
- Journal / source
- The Indian Journal of Medical Research
- Publisher
- Scientific Scholar
- Volume
- 163
- Issue
- 1
- Pages
- 129–130
- Publication date
- 28 February 2026
- Language
- EN