Adjuvant Hemadsorption Therapy in the Management of Refractory Septic Shock

Indian Journal of Nephrology 2026 Open access

Read full text
Authors: Mehul S. Shah, Rushi V Deshpande, Shreyans Rai, Gauri Pathare, Rohan P Parekh, Sheetal Gupta, Harshal Shah, Charmaine Almeida, Nitin Deote, Rahul Anil Pandit
DOI: 10.25259/ijn_279_2025
Cited by: 0
References: 30

Abstract

Background Sepsis and septic shock remain global healthcare challenges, with mortality reaching up to 80% upon progression to refractory septic shock (RSS) and multi-organ dysfunction (MOD). A dysregulated immune response, characterized by a cytokine storm, is associated with increased mortality. This study evaluated the effectiveness of early hemadsorption to remove inflammatory mediators on survival and hospitalization duration in patients with RSS. Materials and Methods This retrospective study included 112 patients with refractory septic shock (RSS) treated with hemadsorption. Patients were divided into early (

Fields of Study & Subjects

Acute Kidney Injury Research Sepsis Diagnosis and Treatment Immune Response and Inflammation

Publication details

Journal / source
Indian Journal of Nephrology
Volume
36
Pages
455–460
Publication date
7 January 2026
Language
EN