Breaking the sheet: A simple twist to improve the cell suspension retention in non-cultured epidermal cell suspension using a pixelated collagen dressing

Non-cultured epidermal cell suspension is an established surgical treatment for stable vitiligo; however, optimal retention of the applied cell suspension at the recipient site remains a technical challenge. Conventional use of a single collagen sheet may result in peripheral pooling of cells, uneven repigmentation, and difficulty in dressing anatomically contoured areas. We describe a simple modification wherein the collagen dressing is divided into multiple small, uniformly sized pieces and evenly applied over the dermabraded recipient site. This technique improves uniform cell retention, minimizes pooling, adapts better to irregular surfaces, and facilitates homogeneous and aesthetically favorable repigmentation.