MORPHOMETRIC AND CYTOCHEMICAL CHANGES IN THE JEJUNUM OF 5-DAY RATS BORN FROM FEMALES WHO CONSUMED ETHANOL DURING PREGNANCY

Alcohol consumption by expectant mothers during pregnancy has an extremely negative impact on the future offspring, causing serious changes in internal organs. Objective. To identify the negative effects of prenatal alcoholization on the jejunum of the offspring of rats that developed under such conditions. Material and methods. The study material was the middle part of the jejunum. A set of histological and histochemical methods with subsequent morphometric and statistical analysis was used. Results. A decrease in the height of the microvillous epithelium of the villi and crypts of animals in the "alcohol" group, as well as a decrease in the area and perimeter of the epithelial cells nuclei were revealed. Cytochemical properties changed mainly in the epithelial cells of the villi. Conclusions. Antenatal alcoholization causes histological and cytochemical changes in the epithelial cells of the villi and crypts of the rat jejunum.