Electron Microscopy Analysis of Circulating Particles from cf-mtDNA-enriched Gold Top Serum

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Authors: Alexandra Volos, Soah Grace Franklin, Jeremy Michelson, Shannon Rausser, Jonathan R. Brestoff, Martin A. Picard
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Abstract

This dataset contains transmission electron microscopy (TEM) imagery and morphometric analysis specific to gold top serum collected from ten healthy participants (5 females, 5 males). As part of a larger study investigating cell-free mitochondrial DNA (cf-mtDNA) and extracellular mitochondria (ex-Mito), this subset focuses on characterizing circulating double-membrane particles and extracellular vesicles isolated via centrifugation and size-exclusion chromatography. These data contribute to a biofluid-specific inventory challenged with distinguishing naked cf-mtDNA from potential mitochondrial transfer mechanisms.

Fields of Study & Subjects

Extracellular vesicles in disease Mitochondrial Function and Pathology Cancer Genomics and Diagnostics

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Language
EN
Document type
Dataset